Comparison of coronary artery lesions between Uygur and Han nationality hypertension patients with coronary heart disease
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摘要: 目的:探讨维吾尔族与汉族高血压伴冠心病(CHD)患者的冠状动脉(冠脉)病变特点。方法:回顾性分析600例维吾尔族与汉族高血压患者行选择性冠脉造影确诊为CHD的病历资料,对其冠脉病变特点加以对比研究;冠脉病变程度用病变部位、支数、分型及病变Gensini总积分表示。结果:维吾尔族组左回旋支病变发生率高于汉族组(59.5%∶46.0%,P<0.05),单支病变发生率明显低于汉族组(28.9%∶37.9%,P<0.05),而3支病变发生率显著高于汉族组(44.3%∶25.6%,P<0.05);维吾尔族组A型病变发生率明显低于汉族组(40.9%∶62.1%,P<0.05),而C型病变发生率显著高于汉族组(32.6%∶15.2%,P<0.05);维吾尔族组Gensini总积分高于汉族组[(43.1±33.0)∶(28.6±25.9),P<0.05]。结论:维吾尔族高血压伴CHD患者以3支病变率高,C型病变居多,冠脉病变程度较汉族患者严重。Abstract: Objective:To study the characteristics of coronary artery lesions of coronary heart disease(CHD) in Uygur and Han nationality hypertension patients. Method:A total of 600 hypertension patients with CHD in our hospital were divided into Han group(n=309) and Uygur group(n=291).The coronary lesions were evaluated by location,quantity,type and Gensini scores. Result:The incidence of left circumflex branch lesion was significantly higher in Uygur group than that in Han group(59.5%∶46.0%,P<0.05).The incidence of single branch lesion in Uygur group was lower than that in Han(28.9%∶37.9%,P<0.05),but the incidence of 3-vessel lesions was significantly higher(44.3%∶25.6%,P<0.05).Compared with Han group,C-type lesion rate was higher(32.6%∶15.2%,P<0.05) and A-type lesion rate was lower(40.9%∶62.1%,P<0.05) in Uygur group.Gensini score of Uygur group was significantly higher than those of Han group [(43.1±33.0)∶(28.6±25.9),P<0.05]. Conclusion:Uygur hypertension patients with CHD have more severe coronary artery lesions than Han patients,have high rates of 3-branch and C-type lesions.
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Key words:
- hypertension /
- coronary artery disease /
- ethnic differences /
- coronary angiography
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[1] CHOBANIAN A V,BAKRIS G L,BLACK H R,et al.Seventh report of the Joint National Committee on prevention,detection,evaluation,and treatment of highblood pressure[J].Hypertension,2003,42:1206-1252.
[2] 中国成人血脂异常防治指南制定联合委员会.中国成人血脂异常防治指南[J].中华心血管病杂志,2007,35(5):390-394.
[3] WOODWARD M,HUXLEY H,LAM T H,et al.A comparison of the associations between risk factorsand cardiovascular disease in Asia and Australasia[J].Eur J Cardiovasc Prev Rehabil,2005,12:484-491.
[4] MARC S S,GAVIN J B,DRAZNER M H,et al.Influence of race on death and ischemic complications inpatients with non-ST-elevation acute coronary syndromes despite modern,protocol-guided treatment[J].Circulation,2005,111:1217-1224.
[5] SAUNDERS E,OFILI E.Epidemiology of athero-thrombotic disease and the effectiveness and risks ofantiplatelet therapy:race and ethnicity considerations[J].Cardiol Rev,2008,16:82-86.
[6] 王薇,赵冬,刘静,等.中国35-64岁人群心血管疾病危险因素与发病的前瞻性研究[J].中华心血管病杂志,2003,31(12):902-908.
[7] 崔兰,王贵亮.延边地区CHD患者冠状动脉造影结果分析[J].中国老年学杂志,2008,28(11):257-280.
[8] 杨胜利,何秉贤,何作云,等.新疆维汉两民族CHD患者载脂蛋白E基因多态性研究[J].中国微循环,2004,8(1):21-25.
[9] 郭永和,张维君,周玉杰,等.冠状动脉造影患者心血管危险因素与冠状动脉病变程度的相关性分析[J].中华心血管病杂志,2005,33(5):415-418.
[10] 罗仁,茶春喜,姚建平,等.维吾尔族和汉族2型糖尿病合并CHD患者冠状动脉病变的比较[J].中国糖尿病杂志,2010,18(4):270-272.
[11] SLATER J,SELZER F,DORBALA S,et al.Ethnicdifferences in the presentation treatment strategy and outcomes of percutaneous coronary intervention(a reportfrom the national heart,lung,and blood institute dynamic registry)[J].Am J Cardiol,2003,92:773-778.
[12] 徐东进,江时森,陈绍良,等.中国人与澳大利亚人冠状动脉病变规律的对比研究[J].医学研究生学报,2006,9(10):919-921.
[13] 罗仁,郭敏,茶春喜,等.维吾尔族与汉族心肌梗死患者冠脉病变的临床研究[J].右江医学,2009,37(1):4-6.
[14] 江时森,吕磊,CRAG J,等.中国人与澳大利亚人冠状动脉病变对比研究[J].中华心血管病杂志,2007,35(5):447-450.
[15] 范印文,锦兰,贺宙斌,等.锡伯族和汉族CHD患者颈动脉粥样硬化及冠状动脉病变对比分析[J].中国动脉硬化杂志,2010,18(4):300-302.
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