增强型体外反搏对冠心病患者氨基末端脑钠肽前体的短期影响

刘凡; 杨石; 何文锦

doi:10.13201/j.issn.1001-1439.2013.05.018

增强型体外反搏对冠心病患者氨基末端脑钠肽前体的短期影响

- 重庆市第一人民医院心内科(重庆, 400010)

详细信息

通讯作者: 何文锦,E-mail:daliufan@sina.com

中图分类号: R541.4

收稿日期: 2012-11-28

Short-term effect of enhanced external counterpalsation on NT-proBNP in patients with coronary heart disease

- Department of Cardiology, the First People's Hospital of Chongqing, Chongqing, 400010, China

More Information

Corresponding author: HE Wenjin, E-mail: daliufan@sina.com

Received Date: 28 November 2012

摘要

摘要: 目的：观察增强型体外反搏（EECP）对冠心病患者血浆中氨基末端脑钠肽前体（NT-proBNP）的短期影响。方法：动态观察64例冠心病患者在EECP前、EECP后1h及EECP后24h的血压、心率、NT-proBNP变化。结果：与EECP前和EECP后24h比较，EECP后1h患者舒张压、NT-proBNP明显增加（均P<0.05），而心率、收缩压差异无统计学意义。结论：EECP治疗可导致冠心病患者短暂的NT-proBNP增加，而24h后可回落至基线水平，故冠心病患者作EECP时应监测其血流动力学的即刻效应，避免心力衰竭加重可能。
- 冠心病 /
- 增强型体外反搏 /
- 氨基末端脑钠肽前体
Abstract: Objective: To observe the change of NT-proBNP before enhanced external counterpalsation(EECP) and 1 h, 24 h after EECP in patients with coronary heart disease(CHD). Method: Sixty-four patients with CHD were enrolled.The blood pressure, heart rate, NT-proBNP were measured before EECP and 1 h, 24 h after EECP. Result: Compare with before EECP and 24 h after EECP, diastolic pressure and NT-proBNP increased significantly 1 h after EECP(P<0.05), but there were no significant differences in heart rate and systolic pressure. Conclusion: EECP therapy in patients with CHD could lead to the increase of NT-proBNP in a short time, but it may go back to the baseline level after 24 h, so the immediate effect in hemodynamics should be monitored in order to avoid the aggravation of heart failure.
- coronary heart disease /
- enhanced external counterpalsation /
- N-terminal pro-B-type natriuretic peptide

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参考文献(6)

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