新疆地区阻塞性睡眠呼吸暂停低通气综合征与冠心病的关系

王钊; 姚晓光; 汪迎春; 李南方

doi:10.13201/j.issn.1001-1439.2014.02.017

新疆地区阻塞性睡眠呼吸暂停低通气综合征与冠心病的关系

- 1. 新疆医科大学(乌鲁木齐, 830000);
- 2. 新疆维吾尔自治区人民医院高血压中心新疆维吾尔自治区高血压研究所
基金项目:
新疆维吾尔自治区重点实验室开放课题资助 No:XJYS0906)

详细信息

通讯作者: 李南方,E-mail:Lnanfang@yahoo.com.cn

中图分类号: R541.4

收稿日期: 2013-08-22

Relationship between coronary heart disease and obstructive sleep apnea hypopnea syndrome in Xinjiang region

- 1. Xinjiang Medical University, Urumqi, 830000, China;
- 2. Hypertension Institute of Xinjiang, Hypertension Center, People's Hospital of Xinjiang Urgur Autonomous Region

More Information

Corresponding author: LI Nanfang, E-mail: Lnanfang@yahoo.com.cn

Received Date: 22 August 2013

摘要

摘要: 目的:探讨新疆地区冠心病与阻塞性睡眠呼吸暂停低通气综合征 (OSAHS) 的关系。方法:连续入选疑似冠心病并伴夜间打鼾的住院患者146例, 根据冠状动脉造影结果分为冠心病组和对照组, 再行整夜睡眠监测, 比较两组患者睡眠呼吸紊乱指数 (AHI)、平均氧饱和度、最低氧饱和度和OSAHS发生情况。结果:冠心病组血糖水平、男性构成比均高于对照组 (均P<0.05);冠心病组较对照组AHI[25.65 (33.0):13.10 (28.0), P=0.004]、清醒次数[(22.81±12.66):(17.48±9.51), P=0.013]、睡眠效率[(72.65±13.73):(66.97±16.25), P=0.032]、中重度OSAHS构成比 (73.53%:43.18%, P=0.001) 均明显增加, 而睡眠潜伏期明显少于对照组[19.50 (41.0):31.50 (76.0), P=0.011]。结论:新疆地区冠心病患者与中重度OSAHS相关, 睡眠结构紊乱可能是导致冠心病的危险因素之一;男性、血糖水平增高亦与冠心病有关。
- 冠心病 /
- 心肌缺血 /
- 阻塞性睡眠呼吸暂停低通气综合征
Abstract: Objective: To investigate the relationship between coronary heart disease (CHD) and obstructive sleep apnea hypopnea syndrome (OSAHS) in Xinjiang region.Method: All 146hospitalized patients with snoring at night were placed into CHD group and control group beased on the coronary angiography.The polysomnography was examined in all patients.AHI, average oxygen saturation, the lowest oxygen saturation and occurrence of OSAHS were monitored and compared between the two groups.Result: Blood glucose levels and constituent ratio of male in CHD group were higher than those in control group (P<0.05).AHI[25.65 (33.0) vs 13.10 (28.0), P=0.004], awakening times[(22.81±12.66) vs (17.48±9.51), P=0.013], sleep efficiency[(72.65±13.73) vs (66.97±16.25), P=0.032]and the proportion of moderate and severe OSAHS (73.53%vs 43.18%, P=0.001) in CHD group were greater than those in control group.Sleep latency in CHD group was less than that in control group[19.50 (41.0) vs 31.50 (76.0), P=0.011].Conclusion: There is close relationship between CHD and OSAHS in Xinjiang hospitalized patients.Disorder of sleep is one of the risk factors that could lead to coronary heart disease.Male and increase of blood glucose levels also relate with CHD.
- coronary heart /
- disease myocardial ischemia /
- obstructive sleep apnea hypopnea syndrome

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