Therapeutic value of intra-aortic balloon pumpin and continuous veno-venous hemofiltration administration in severe acute viral myocarditis
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摘要: 目的:探讨主动脉球囊反搏 (IABP) 及连续性静脉-静脉血液滤过 (CVVH) 在重症急性病毒性心肌炎 (SAVM) 中的疗效。方法:对20例重症急性病毒性心肌炎患者资料进行临床回顾性分析。所有患者均进行心电图、心脏超声、胸片和心肌酶谱、肌钙蛋白、血清N端前体脑钠肽 (NT-BNP) 等心肌损伤标识物检查。根据病情需要, 在常规治疗基础上, 部分患者行IABP, 进行CVVH治疗, 监测治疗前后动脉压、心率等生命体征。结果:与非IABP组比较, IABP组平均压升高, 心率降低, 肾功能改善, 心肌酶谱及NT-BNP明显降低, 心功能改善 (均P<0.05);与非CVVH组比较, CVVH组前述指标同样得到改善 (均P<0.05)。治疗后观察, IABP+CVVH组较单纯IVBP、CVVH组各指标亦显著改善 (均P<0.05)。结论:在急性重症病毒性心肌炎患者治疗中, 应用IABP及CVVH能显著改善预后, 降低死亡率。Abstract: Objective: To evaluate the therapeutic effects of intra-aortic balloon pump (IABP) and continuous veno-venous hemofiltration (CVVH) in treating severe acute viral myocarditis (SAVM).Method: We retrospectively analyzed 26cases of SAVM in our department and reviewed our experiences in treating SAVM.The following clinical variables were compared before and after treatment:patient's vital signs, serum biochemistry, myocardial enzymogram and echocardiography.The patients were divided into IABP group, CVVH group and IABP + CVVH group.Result: The patients'arterial pressure, heart rate, urine output, renal function, heart function and NTBNP were improved more in IABP, CVVH group, and there were significant differents between IABP, CVVH and non-IABP, non-CVVH group (all P<0.05).The results also occurred in IABP+CVVH group.Conclusion: Application of IABP and CVVH in acute severe viral myocarditis with pump failure patients will reduce mortality and improve outcomes.
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