Abstract: Objective: To explore the diagnostic value of OGTT in hypertension combined sugar metabotic abnormalities.Method: All 600 patients with hypertension in hospital were underwent OGTT, and calculated the statistics of new cases of diabetes, postprandial blood sugar and new impaired blood sugar before meal, and detected the fasting C-peptide levels of blood lipids, etc.Meanwhile, we analyzed the data about sex, age, family history of diabetes mellitus and dyslipidemia in the subgroup.Result: After OGTT, the occurrence rate of diabetes increased from 23% to 34%, postprandial blood sugar was 22%, blood sugar impaired before meal increased from 2% to 6%, and total sugar metabolic abnormalities was 62%.There was no visible difference between men and women patients of the hypertension combined sugar metabolic abnormalities (63.8% vs 61.0%, P=0.281), there were more patients above 40 years old who suffered from sugar metabolic abnormalities than those below 40years old (73.6%vs 52.2%, P=0.023), and more patients with family history of diabetes mellitus suffered from sugar metabolic abnormalities than those without family history of diabetes mellitus (83.5% vs 43.1%, P=0.008).Patients with lipoprotein abnormalities easily sufferd from glucose metabolic disease (70.4% vs 63.6%, P=0.036).Cpeptide levels in sugar metabolic abnormalities group were abviously higher than that in sugar metabolism normal group[(615±24) pmol/L vs (285±32) pmol/L, P=0.009].Conclusion: Patients with hypertension should regularly undergo OGTT, especially the middle-aged, elderly patients with family history of diabetes mellitus and sugar metabolic abnormalities.