华法林与阿司匹林对慢性重度心力衰竭合并持续性房颤患者临床疗效的比较

张洪君; 谢年谨

doi:10.13201/j.issn.1001-1439.2014.07.024

华法林与阿司匹林对慢性重度心力衰竭合并持续性房颤患者临床疗效的比较

张洪君^1, ,,
谢年谨²

- 1 宝安区石岩人民医院心内科(广东深圳, 518108);
- 2 广东省人民医院心内科

详细信息

通讯作者: 张洪君,E-mail:szzhanghongjun@163.com

中图分类号: R541.6

收稿日期: 2014-02-11

Comparison between the effects of Warfar and aspirin in chronic severe heart failure patients with persistent atrial fibrillation

ZHANG Hongjun^1, ,,
XIE Nianjin²

- 1 Department of Cardiology, The Baoan District Shiyan People's Hospital, Shenzhen, Guangdong, 518108, China;
- 2 Department of Cardiology, People's Hospital in Guangdong Provence

More Information

Corresponding author: ZHANG Hongjun, E-mail: szzhanghongjun@163.com

Received Date: 11 February 2014

摘要

- 华法林 /
- 阿司匹林 /
- 心力衰竭 /
- 心房颤动
Abstract: In this study we explored whether warfarin is superior to aspirin for clinical efficacy in chronic severe heart failure patients with persistent atrial fibrillation.The result showed that incidence of cardioversion of atrial fibrillation and maintainance of sinus rhythem in warfarin group were significantly higher than aspirin group.Compared with aspirin, the incidence of primary end point and embolism were significantly reduced by warfarin.So the clinical efficacy of warfarin is better than aspirin in chronic severe heart failure patients with persistent atrial fibrillation.
- warfarin /
- aspirin /
- heart failure /
- atrial fibrillation

HTML全文

参考文献(9)

[1]	BUI A L, GRAU-SEPULVEDA MV, HERNANDEZ A F, et al.Admission heart rate and in-hospital outcomes in patients hospitalized for heart failure in sinus rhythm and in atrial fibrillation[J].Am Heart J, 2013, 165:567-574.
[2]	SCHMIEGELOW M D, PEDERSEN O D, KøBER L, et al.Incidence of atrial fibrillation in patients with either heart failure or acute myocardial infarction and left ventricular dysfunction:a cohort study[J].BMC Cardiovasc Disord, 2011, 11:19-22.
[3]	QI W.Retrospective investigation of hospitalised patients with atrial fibrillation in mainland China[J].Int J Cardiol, 2005, 105:283-237.
[4]	AHMED A, THORNTON P, PERRY G J, et al.Impact of atrial fibrillation on mortality and readmission in older adults hospitalized with heart failure[J].Eur J Heart Fail, 2004, 6:421-426.
[5]	SHANTSILA E, LIP G Y.Stroke prevention in atrial fibrillation in heart failure[J].Heart Fail Clin, 2013, 9:427-435.
[6]	LIP G Y, NIEUWLAAT R, PISTERS R, et al.Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach:the euro heart survey on atrial fibrillation[J].Chest, 2010, 137:263-272.
[7]	LAKSHMINARAYAN K, SOLID C A, COLLINS A J, et al.Atrial fibrillation and stroke in the general medicare population:a 10-year perspective (1992 to 2002)[J].Stroke, 2006, 37:1969-1974.
[8]	张源, 殷跃辉, 梅霞.心房颤动抗凝治疗新进展[J].心血管病学进展, 2012, 33 (6):743-747.
[9]	黄军章, 李红昆, 陆永光, 等.高龄持续性心房纤颤患者不同剂量阿司匹林与华法林抗栓疗效及安全性比较[J].岭南心血管病杂志, 2012, 18 (4):357-359.