老年高血压合并缺血性心脏病患者舒张压下降过程中“J形曲线”现象的分析

张丽

doi:10.13201/j.issn.1001-1439.2015.08.009

老年高血压合并缺血性心脏病患者舒张压下降过程中“J形曲线”现象的分析

张丽^,

- 南阳医学高等专科学校第一附属医院心内二科(河南南阳, 473058)

详细信息

通讯作者: 张丽,E-mail:liutao197810@163.com

中图分类号: R544.1

收稿日期: 2014-09-19

The analysis of “J curve” phenomenon during the process of reduction in diastolic blood pressure for aged patients with ischemic heart disease

ZHANG Li^,

- Department of Cardiology, the First Affiliated Hospital of Nanyang Medical College, Nanyang, Henan, 473058, China

More Information

Corresponding author: ZHANG Li, E-mail: liutao197810@163.com

Received Date: 19 September 2014

摘要

摘要: 目的：探讨老年原发性高血压合并缺血性心脏病患者不同舒张压（DBP）水平与心脑血管事件发生的关系。方法：回顾性分析750例老年原发性高血压合并缺血性心脏病患者，按不同DBP水平以5 mmHg （1 mmHg=0.133 kPa）为界限分成6组：1组DBP<70 mmHg；2组DBP 70~75 mmHg；3组DBP 76~80 mmHg；4组DBP 81~85 mmHg；5组DBP 86~90 mmHg；6组DBP >90 mmHg，统计终点事件数，采用SPSS 16.0软件和Cox比例风险模型分析，并绘制曲线图进行趋势分析。结果：与4组比较，1组、2组、5组和6组患者心脑血管事件发生的相对风险（RR值）明显增加，差异有统计学意义（P<0.01）；校正危险因素后，与4组比较，1组、5组和6组患者心脑血管事件发生的相对风险分别增加67%、173%及222%（P<0.05、P<0.01）。结论：老年高血压合并缺血性心脏病患者DBP应降到合理的范围，DBP下降过程中"J形曲线"现象是存在的。
- 老年原发性高血压病 /
- 心脑血管事件 /
- J形曲线
Abstract: Objective: To investigate the correlation between diastolic blood pressure level and cerebrovascular events of aged patients with hypertension and ischemic heart disease.Method: The retrospective analysis observes 750 cases of elderly patients with hypertension and ischemic heart disease.According to the different levels of diastolic blood pressure, patients with hypertension can be divided into 6 groups with 5 mmHg(1 mmHg=0.133 kPa) as the boundary:1st group with DBP<70 mmHg, 2nd group with DBP from 70 mmHg to 75 mmHg, 3th group with DBP from 76 mmHg to 80 mmHg, 4th group with DBP from 81 to 85 mmHg, 5th group with DBP from 86 to 90 mmHg and 6th group with DBP>90 mmHg. Statistics the number of endpoint events.Statistical analysis is performed using SPSS16.0 software system and Cox proportional hazard model. the graph is drawn for trend analysis.Result: Compared to group 4, the relative risks(The value of RR) of cardiovascular and cerebrovascular events in group 1, 2, 5 and 6 were increased significantly. The difference was statistically significant(P<0.01). After risk factor adjustment, the relative risks of cardiovascular and cerebrovascular events in group 1, 5 and 6 increased by 67%, 173% and 222% respectively compared to group 4(P<0.05, P<0.01).Conclusion: The diastolic pressure of elderly patients with hypertension and ischemic heart disease should be reduced to reasonable range, and the "J curve" phenomenon can occur during the process of DBP reduction.
- senile hyperpietic /
- cardiovascular and cerebrovascular events /
- J curve

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