血栓抽吸在急性ST段抬高型心肌梗死患者直接经皮冠状动脉介入治疗中的应用

冯嘉旭; 张卫泽; 王海昌; 孙冬冬

doi:10.13201/j.issn.1001-1439.2016.01.002

血栓抽吸在急性ST段抬高型心肌梗死患者直接经皮冠状动脉介入治疗中的应用

- 1 中国人民解放军第四军医大学附属西京医院心血管内科(西安, 710032);
- 2 中国人民解放军兰州军区兰州总医院心血管内科
基金项目:
国家自然科学基金项目(No.81100579)

详细信息

通讯作者: 孙冬冬,E-mail:wintersun3@gmail.com

中图分类号: R541.4

收稿日期: 2015-09-23

Thrombus aspiration in primary percutaneous coronary intervention for patients with acute ST-segment elevation myocardial infarction

- 1 Department of Cardiology, Xijing Hospital of the Fourth Military Medical University of PLA, Xi'an, 710032, China;
- 2 Department of Cardiolgy, Lanzhou General Hospital of Lanzhou Military Region of PLA

More Information

Corresponding author: SUN Dongdong, E-mail: wintersun3@gmail.com

Received Date: 23 September 2015

摘要

摘要: 急性ST段抬高型心肌梗死患者采用直接经皮冠状动脉介入治疗可以实现及时的心肌机械再灌注。但对于心外膜血管闭塞的患者来说,进行球囊血管成形术和支架置入术可能会导致管腔内的血栓破裂,从而引起心肌再灌注不良和微循环障碍,而血栓抽吸的应用则可以有效地预防远端血管栓塞等不良事件的发生。本综述主要着眼于血栓抽吸在急性ST段抬高型心肌梗死患者临床介入治疗方面的应用,并对其优缺点和相关研究的结果进行讨论。
- 血栓抽吸 /
- 经皮冠状动脉介入治疗 /
- 急性ST段抬高型心肌梗死 /
- 急性冠状动脉综合征
Abstract: Primary percutaneous coronary intervention, through which mechanical reperfusion can be realized in patients with acute ST-segment elevation myocardial infarction, is superior to fibrinolysis in terms of short-term and long-term outcome. But for patients who have an occluded epicardial vessel, balloon angioplasty and stent implantation can cause disruption of the frail thrombus containing lesions, that associated with suboptimal myocardial reperfusion and microcirculatory obstruction. However, the use of thrombus aspiration during primary angioplasty can effectively prevent many adverse events like distal embolization of atherothrombotic material. Here we review the applications of thrombus aspiration in primary percutaneous coronary intervention for patients with acute ST-segment elevation myocardial infarction, and discuss their merits and demerits and the reported results.
- thrombus aspiration /
- percutaneous coronary intervention /
- acute ST-segment elevation myocardial infarction /
- acute coronary syndrome

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