同型半胱氨酸与心血管疾病关系的研究进展

杨英; 杨俊

doi:10.13201/j.issn.1001-1439.2017.02.002

同型半胱氨酸与心血管疾病关系的研究进展

杨英,
杨俊^,

- 三峡大学心血管病研究所三峡大学第一临床医学院心内科(湖北宜昌, 443003)
基金项目:
国家自然科学基金(No:81170133,81200088,81470387)

湖北省首届医学领军人才基金(鄂卫生计发〔2013〕4号)

湖北省科技支撑计划(No:2015BKA340)

详细信息

通讯作者: 杨俊,E-mail:yangjun@ctgu.edu.cn

中图分类号: R541

收稿日期: 2016-08-19

修回日期: 2016-11-18

Progress in the relationship between homocysteine and cardiovascular disease

YANG Ying,
YANG Jun^,

- Department of Cardiology, the First Affiliated Hospital of Three Gorges University, Yichang, 443003, China

More Information

Corresponding author: YANG Jun, E-mail: yangjun@ctgu.edu.cn

Received Date: 19 August 2016

Revised Date: 18 November 2016

摘要

摘要: 同型半胱氨酸(Hcy)是蛋氨酸代谢后形成的细胞毒性代谢产物,以各种形式存在于血液中。大量研究发现,Hcy与心血管疾病的发生、发展密切相关,本文就Hcy的生理功能、Hcy与心血管疾病之间的关系、Hcy致心血管疾病的机制进行综述。
- 同型半胱氨酸 /
- 心血管疾病 /
- 机制
Abstract: Homocysteine (Hcy) is a cellular toxic metabolite formed after methionine metabolism, and it exists in the blood in various forms. A large number of studies have found that Hcy is closely related to the occurrence and development of cardiovascular disease. This article reviews the physiological role of Hcy, the relationship between Hcy and cardiovascular disease, and the mechanism of Hcy induced cardiovascular disease.
- homocysteine /
- cardiovascular disease /
- mechanism

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参考文献(33)

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