急性心肌梗死患者GRACE评分与实验室指标的相关性

杨利娇; 王虹; 丁振江; 王文丰; 张一达; 袁月敏; 韩婷婷

doi:10.13201/j.issn.1001-1439.2017.02.010

急性心肌梗死患者GRACE评分与实验室指标的相关性

- 承德医学院附属医院心血管内科(河北承德, 067000)

详细信息

通讯作者: 王虹,E-mail:wanghong3721@163.com

中图分类号: R542.2

收稿日期: 2016-09-22

Correlation of GRACE score and laboratory index in patients with acute myocardial infarction

- Department of Cardiology, Affiliated Hospital of Chengde Medical College, Chengde, 067000, China

More Information

Corresponding author: WANG Hong, E-mail: wanghong3721@163.com

Received Date: 22 September 2016

摘要

摘要: 目的:研究急性心肌梗死(AMI)患者GRACE评分与实验室检查指标间的相关性。方法:回顾性分析2014-01-2016-09我院心内科收治的AMI患者186例,其中ST段抬高型心肌梗死(STEMI)125例(STEMI组),非ST段抬高型心肌梗死(NSTEMI)61例(NSTEMI组)。计算患者入院时GRACE评分,并将患者分为低危组、中危组、高危组。收集患者一般资料和实验室指标,分析GRACE评分与实验室指标间的相关性。结果:年龄、性别、饮酒史、红细胞压积、GRACE评分在STEMI组与NSTEMI组间差异有统计学意义(P＜0.05),根据GRACE评分、红细胞压积、年龄绘制ROC曲线下面积分别为0.626[95%可信区间(CI):0.538~0.713,P＜0.01]、0.633(95%CI: 0.542~0.724,P＜0.01)、0.665(95%CI:0.578~0.752,P＜0.01),3者联合起来ROC曲线下面积为0.678(95%CI:0.592~0.763,P＜0.01)。性别、吸烟、饮酒史、D-二聚体、纤维蛋白原降解产物、红细胞压积、红细胞分布宽度、红细胞平均体积、年龄在GRACE评分低、中、高危组间差异有统计学意义(P＜0.05),相关性分析显示,D-二聚体、纤维蛋白降解产物、红细胞压积、红细胞分布宽度、红细胞平均体积、血小板压积、血小板平均体积、年龄与GRACE评分的相关性差异有统计学意义(P＜0.05),多元线性回归显示年龄和纤维蛋白原降解产物与GRACE评分独立相关。结论:STEMI组与NSTEMI组患者年龄、性别、饮酒史、红细胞压积、GRACE评分间有差别,实验室检查指标与GRACE评分间有明显相关性。
- 急性心肌梗死 /
- GRACE评分 /
- D-二聚体 /
- 相关性
Abstract: Objective:To investigate the correlation between GRACE score and laboratory Index in patients with AMI. Method: There were 186 patients with AMI in this study, including 125 patients with ST-elevation myocardial infarction(STEMI)and 61 patients with non ST-elevation myocardial infarction(NSTEMI). The baseline characteristics and laboratory index were cllected in all patients on admission. According to GRACE score, patients were divided into low, middle, high risk groups. Result: Age, sex, drinking, PRBC and GRACE score were different in STEMI and NSTEMI(P＜0.05). The areas under the ROC curve in terms of GRACE score, PRBC, age and combined of three were 0.626(95%CI:0.538~0.713,P＜0.01), 0.633(95%CI:0.542~0.724,P＜0.01), 0.665(95%CI:0.578~0.752,P＜0.01),0.678(95%CI:0.592~0.763, P＜0.01), respectively. Sex, smoking, drinking, D-dimer, fibrinogen degradation products, PRBC, RDW, MCV, age were different among low, middle, high GRACE score groups(P＜0.05). There were positive correlation between D-dimer, fibrinogen degradation products, PRBC, RDW, MCV, PCT, MPV, age and GRACE score(P＜0.05). Multiple linear regression analysis showed that age, fibrinogen degradation products were independent influent factors of GRACE score. Conclusion: Age, sex, drinking, PRBC, GRACE score are different in STEMI and NSTEMI. There are great correlations between GRACE score and laboratory index.
- acute myocardial infarction /
- GRACE score /
- D-dimer /
- correlation

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