Tpe在急性心肌梗死中的临床意义

李路; 彭瑜; 张钲

doi:10.13201/j.issn.1001-1439.2017.05.004

Tpe在急性心肌梗死中的临床意义

- 兰州大学第一附属医院(兰州, 730000)

详细信息

通讯作者: 张钲,E-mail:zhangccu@163.com

中图分类号: R541.4

收稿日期: 2016-10-22

The clinical significance of Tpe in acute myocardial infarction

- The First Hospital of Lanzhou University, Lanzhou, 730000, China

More Information

Corresponding author: ZHANG Zheng, E-mail: zhangccu@163.com

Received Date: 22 October 2016

摘要

摘要: 心律失常是急性心肌梗死(AMI)患者发病后早期常见的并发症,而AMI患者发生心律失常的预测因子一直是临床医师关注的热点。近些年发现心肌缺血可显著影响心肌细胞的离子通道,造成缺血心肌复极离散度(TDR)的增大,并且缺血引起的自主神经紊乱进一步增大了TDR,并触发2相折返,引发室性心律失常。与QT、QTd相比,Tpe在恶性心律失常上具有更好的预测价值,深入了解Tpe与心律失常关系及作用机制,对有效防治心律失常有重要的临床意义。
- Tpe /
- 心肌梗死 /
- 心律失常
Abstract: Arrhythmia is a common complication of acute myocardial infarction (AMI), and clinical physicians has always pay close attention to the predictors of arrhythmia in AMI patients. In recent years, many researches have found that myocardial ischemia has significant effects on the ion channel of myocardial cells, leading to increase the transmural dispersion of repolarization (TDR) of ischemia myocardium, and the autonomic nerve disorder caused by ischemia, further increases the TDR, finally triggers the phase-2 reentry, and result in ventricular arrhythmia. Compared with QT and QTd, Tpe has been thought as a better predictor in the malignant arrhythmia. We summarized the mechanisms and relationship between Tpe and arrhythmia, which may produce a positive clinical significance in the effective prevention and treatment of arrhythmia.
- Tpe /
- myocardial infarction /
- arrhythmia

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参考文献(28)

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