Arrhythmia and cardiomyopathy related chemokine networks:A review of their development
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摘要: 趋化因子是一类能介导细胞定向迁移的细胞因子,大量研究表明趋化因子参与心血管损伤反应的各个阶段。同时,趋化因子作为一种可潜在预测心血管风险的生物学标志广受关注,并可能是治疗心血管疾病的潜在靶点。本文介绍趋化因子网络与心律失常和心肌病的研究进展。Abstract: Chemokines are a subgroup of cytokines with the specific function of cells trafficking.Plenty of studies have shown chemokines were closely associated with cardiovascular diseases and involved in all stages of cardiovascular response to injury.Moreover, chemokines are focus of intense interest for being used as biomarkers to predict risk of cardiovascular events in people and as possible new therapeutic targets.Here, we will discuss in detail about their roles in the progression of cardiomyopathy and arrthythmia.
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Key words:
- chemokines /
- inflammation /
- dilated cardiomyopathy /
- arrthythmia
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