心律失常和心肌病相关趋化因子网络研究进展

刘萧; 郭琳娟; 洪葵

doi:10.13201/j.issn.1001-1439.2017.09.021

心律失常和心肌病相关趋化因子网络研究进展

- 1 南昌大学第二附属医院心内科(南昌, 330006);
- 2 南昌大学第二附属医院分子医学重点实验室
基金项目:
国家自然科学基金 (No:8153000545)

详细信息

通讯作者: 洪葵, E-mail:hongkui88@163.com

中图分类号: R541.7,R542.2

收稿日期: 2017-02-06

Arrhythmia and cardiomyopathy related chemokine networks:A review of their development

- 1 Department of Cardiology, the Second Affiliated Hospital of Nanchang University, Nanchang, 330006, China;
- 2 Key Laboratory of Molecular medicine, the Second Affiliated Hospital of Nanchang University

More Information

Corresponding author: HONG Kui, E-mail: hongkui88@163.com

Received Date: 06 February 2017

摘要

摘要: 趋化因子是一类能介导细胞定向迁移的细胞因子,大量研究表明趋化因子参与心血管损伤反应的各个阶段。同时,趋化因子作为一种可潜在预测心血管风险的生物学标志广受关注,并可能是治疗心血管疾病的潜在靶点。本文介绍趋化因子网络与心律失常和心肌病的研究进展。
- 趋化因子 /
- 炎症 /
- 扩张型心肌病 /
- 心律失常
Abstract: Chemokines are a subgroup of cytokines with the specific function of cells trafficking.Plenty of studies have shown chemokines were closely associated with cardiovascular diseases and involved in all stages of cardiovascular response to injury.Moreover, chemokines are focus of intense interest for being used as biomarkers to predict risk of cardiovascular events in people and as possible new therapeutic targets.Here, we will discuss in detail about their roles in the progression of cardiomyopathy and arrthythmia.
- chemokines /
- inflammation /
- dilated cardiomyopathy /
- arrthythmia

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