缺血预处理预防经桡动脉冠状动脉造影对桡动脉的损伤

吴万里; 潘朝锌; 王庆高; 杨清华; 张振千; 梁逸强; 温志浩; 黄明剑

doi:10.13201/j.issn.1001-1439.2018.04.011

缺血预处理预防经桡动脉冠状动脉造影对桡动脉的损伤

- 广西中医药大学第一附属医院心内科一病区(南宁, 530023)

详细信息

通讯作者: 吴万里,E-mail:1135336955@qq.com

中图分类号: R445

收稿日期: 2018-01-06

Effects of ischemic preconditioning on injury of radial artery after transradial coronary angiography

- Department of Cardiology, the First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine, Nanning, 530023, China

More Information

Corresponding author: WU Wanli, E-mail: 1135336955@qq.com

Received Date: 06 January 2018

摘要

摘要: 目的:探讨经桡动脉冠状动脉造影 (CAG) 对桡动脉的损伤及其预防方法。方法:将择期经桡动脉CAG的150例患者随机分为对照组 (75例) 和试验组 (75例)。试验组患者用血压计袖带缠绕于右上臂并充气达200mmHg (1mmHg=0.133kPa), 持续5min后放气, 重复3次, 每次间隔5min, 然后经桡动脉CAG;对照组不作预处理, 直接经桡动脉CAG。术前和术后1周, 用彩色多普勒超声诊断仪观察桡动脉远端的变化。结果:与术前比较, 两组术后桡动脉内中膜厚度均增加[对照组:(0.29±0.06) mm:(0.52±0.12) mm, P＜0.05;试验组:(0.30±0.06) mm:(0.42±0.09) mm, P＜0.05], 内径均变小[对照组:(2.46±0.44) mm:(2.05±0.48) mm, P＜0.05;试验组:(2.47±0.50) mm:(2.23±0.51) mm, P＜0.05], 血流峰值均增大[对照组:(0.50±0.10) m/s:(0.57±0.11) m/s, P＜0.05;试验组:(0.50±0.11) m/s:(0.53±0.11) m/s, P＜0.05]。与对照组比较, 试验组术后桡动脉内中膜厚度更小, 内径更大, 血流峰值更小 (均P＜0.05)。结论:经桡动脉CAG对桡动脉远端有损伤, 缺血预处理可减轻其损伤。
- 缺血预处理 /
- 桡动脉 /
- 冠状动脉造影 /
- 损伤
Abstract: Objective: To explore effects of ischemic preconditioning on injury of radial artery after transradial coronary angiography (CAG).Method: A total of 150 patients who received elective transradial CAG were randomly divided into observation group (n=75) and control group (n=75).In observation group, patient were wrapped around the right upper arm with a cuff of sphygmomanometer and inflated up to 200 mmHg (1 mmHg=0.133 kPa), lasted for 5 minutes, then deflated.This process was repeated 3 times, each interval time was five minutes, then patients were sent to the cath lab for transradial CAG.In control group, patients received transradial CAG without ischemic preconditioning.Before and 1 week after transradial CAG, changes of distal radial artery were observed with color Doppler ultrasound.Result: After transradial CAG in both groups, the intima-media thickness of radial artery was increased [control group:(0.29±0.06) mm vs (0.52±0.12) mm, P＜0.05;observation group:(0.30±0.06) mm vs (0.42±0.09) mm, P＜0.05], the inner diameter was decreased [control group:(2.46±0.44) mm vs (2.05±0.48) mm, P＜0.05;observation group:(2.47±0.50) mm vs (2.23±0.51) mm, P＜0.05] and the peak of blood flow was increased [control group:(0.50±0.10) m/s vs (0.57±0.11) m/s, P＜0.05;observation group:(0.50±0.11) m/s vs (0.53±0.11) m/s, P＜0.05]. Compared with those in control group, the intima-media thickness of radial artery was smaller, the inner diameter was larger and the blood flow peak was smaller in observation group (all P＜0.05).Conclusion: The transradial CAG can damage the distal of radial artery, and the ischemic preconditioning can prevent the injury.
- ischemic preconditioning /
- radial artery /
- coronary angiography /
- injury

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