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摘要: 自噬作为一种高度保守的自我保护机制在多种心血管疾病特别是动脉粥样硬化、心肌缺血再灌注损伤、心力衰竭中发挥重要作用, 并与内质网和线粒体产生的活性氧簇 (ROS) 相互作用, 全面了解二者间关系可能为预防和治疗心血管疾病提供新的策略。Abstract: Autophagy, as a highly conserved mechanism of self-protection, plays an important role in many cardiovascular diseases, especially in atherosclerosis, myocardial ischemia reperfusion injury and heart failure.With the endoplasmic reticulum and mitochondria (ROS) interaction, a comprehensive understanding of the relationship between the two may provide a new strategy for the prevention and treatment of cardiovascular disease.
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Key words:
- autophagy /
- oxidative stress /
- cardiovascular diseases
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