Chinese guidelines for diagnosis and treatment of dilated cardiomayopathy:innovation and transformation
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摘要: 《中国扩张型心肌病诊断和治疗指南》依据创新与转化的研究成果, 提出扩张型心肌病 (DCM) 的病因诊断, 临床研究证实抗心肌抗体可以预测DCM猝死和死亡。该指南提出针对DCM病因的免疫学治疗, 临床试验证实通过药物阻止抗体、免疫吸附抗体和免疫调节治疗可以改善DCM患者心功能和降低病死率。Abstract: According to the innovative and transformative results in Chinese clinical trials, the"2018 Chinese guidelines for diagnosis and treatment of dilated cardiomyopathy (DCM) "proposes the etiological diagnosis of DCM.The clinical studies have confirmed that anti-heart autoantibodies can predict the sudden death and mortality of DCM.Therefore, the guidelines advance a series of noval immunological therapies against the etiological diagnosis of DCM.Those therapies, including blocking antibody by drugs, immuno-absorption antibody and immuno-regulation therapy, are effective in improving cardiac function and decreasing mortality in patients with DCM.
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Key words:
- dilated cardiomyopathy /
- anti-heart autoantibodies /
- immunological therapy
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