Abstract: Objective:We investigated the characteristics of ascending aorta elasticity in patients with hypertrophic cardiomyopathy by echocardiography and analyzed the changes of ascending aortic function in patients with hypertrophic cardiomyopathy.Method:The patients with hypertrophic cardiomyopathy who received echocardiographic examination in our hospital were divided into obstructive group (HOCM group) and non-obstructive group (HNOCM group) according to the pathological changes.The healthy persons were selected as the control group.Each group had 30 cases.We compared echocardiographic parameters and ascending aortic elastic parameters among the three groups.Result:Among the HOCM group, HNOCM group and control group, the ascending aortic strain index, dilation and early diastolic velocity increased gradually, while ascending aortic stiffness index decreased, which were statistically significant (P＜0.05).The late diastolic movement velocity in HOCM and HNOCM groups were significantly lower than those in control group, and the systolic velocity of ascending aortic anterior wall in HOCM group was lower than that in control group (P＜0.05).Conclusion:The vascular elasticity of ascending aorta was decreased in hypertrophic cardiomyopathy patients, especially in obstructive hypertrophic cardiomyopathy patients.