体外心脏震波治疗难治性心绞痛新进展

于亚梅; 余云华; 郑兴

doi:10.13201/j.issn.1001-1439.2019.03.004

体外心脏震波治疗难治性心绞痛新进展

- 1. 上海市同仁医院心内科(上海, 200050);
- 2. 海军军医大学附属长海医院;
- 3. 解放军福州总医院干部病房二科
基金项目:
上海市科委科技支撑项目（No：13411950302）

详细信息

通讯作者: 郑兴,E-mail:zhengxing57530@163.com

中图分类号: R541.4

收稿日期: 2018-08-23

Progression of the cardiac shock wave therapy in treatment of refractory angina pectoris

- 1. Department of Cardiovasology, Tongren Hospital, Shanghai, 200050, China;
- 2. Department of Cardiovasology, Changhai Hospital, Second Military Medical University;
- 3. Department of Geriatrics, Fuzhou General Hospital of Liberation Army

More Information

Corresponding author: ZHENG Xing, E-mail: zhengxing57530@163.com

Received Date: 23 August 2018

摘要

摘要: 传统的冠心病治疗方法为药物治疗联合冠状动脉介入治疗和（或）冠状动脉旁路移植术。但仍有部分患者经过严格上述治疗后心绞痛仍发作频繁或逐渐加重，严重影响了患者的生活质量或预后。因此，为这些患者寻找一种新的治疗方法至关重要。体外心脏震波治疗是近年来开展的一项新的治疗方法，已被用于缺血性心脏疾病的治疗。本文就体外心脏震波在难治性心绞痛治疗中的应用进行综述。
- 难治性心绞痛 /
- 体外心脏震波治疗
Abstract: The traditional treatments of coronary heart disease are drug therapy combined with percutaneous coronary intervention or coronary artery bypass grafting.However, some patients still suffer from recurrent or aggravated angina after strict treatment, which seriously affects their quality of life or prognosis.So, it is important to find a new treatment for these patients.Cardiac shock wave therapy is a new method developed in recent years and has been used in the treatment of ischemic heart disease.This review summarizes the application of cardiac shock wave therapy in the treatment of refractory angina pectoris.
- refractory angina pectoris /
- cardiac shock wave therapy

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参考文献(36)

[1]	Kornowski R.Refractory myocardial angina and determinants of prognosis[J].Catheter Cardiovasc Interv, 2010, 75(6):892-894.
[2]	Henry TD, Satran D, Hodges JS, et al.Long-term survival in patients with refractory angina[J].Eur Heart J, 2013, 34(34):2683-2688.
[3]	Alunni G, Barbero U, Vairo A, et al.The beneficial effect of extracorporeal shockwave myocardial revascularization:Two years of follow-up[J].Cardiovasc Revasc Med, 2017, 18(8):572-576.
[4]	Abe Y, Ito K, Hao K, et al.Extracorporeal low-energy shock-wave therapy exerts anti-inflammatory effects in a rat model of acute myocardial infarction[J].Circ J, 2014, 78(12):2915-2925.
[5]	Fu M, Sun CK, Lin YC, et al.Extracorporeal shock wave therapy reverses ischemia-related left ventricular dysfunction and remodeling:molecular-cellular and functional assessment[J].PLoS One, 2011, 6(9):e24342.
[6]	Lei PP, Tao SM, Shuai Q, et al.Extracorporeal cardiac shock wave therapy ameliorates myocardial fibrosis by decreasing the amount of fibrocytes after acute myocardial infarction in pigs[J].Coron Artery Dis, 2013, 24(6):509-515.
[7]	Wang J, Zhou C, Liu L, et al.Clinical effect of cardiac shock wave therapy on patients with ischaemic heart disease:a systematic review and meta-analysis[J].Eur J Clin Invest, 2015, 45(12):1270-1285.
[8]	郑志远, 王海东, 许良春, 等.体外心脏震波治疗系统治疗冠心病的机理及主要结构和工作原理[J].中国医疗设备, 2010, 25(1):47-49.
[9]	西雁, 崔洁, 林贻梅, 等.体外心脏冲击波治疗难治性心绞痛的初步疗效及安全性[J].上海医学, 2009, 32(10):872-875, 835.
[10]	Burneikaite G, Shkolnik E, Celutkiene J, et al.Cardiac shock-wave therapy in the treatment of coronary artery disease:systematic review and meta-analysis[J].Cardiovasc Ultrasound, 2017, 15(1):11.
[11]	Maisonhaute E, Prado C, White PC, et al.Surface acoustic cavitation understood via nanosecond electrochemistry.Part Ⅲ:Shear stress in ultrasonic cleaning[J].Ultrason Sonochem, 2002, 9(6):297-303.
[12]	Apfel RE.Acoustic cavitation:a possible consequence of biomedical uses of ultrasound[J].Br J Cancer Suppl, 1982, 5:140-146.
[13]	周超, 王静, 庞玺倬, 等.体外心脏震波治疗冠心病新进展[J].中国循环杂志, 2015, 30(3):287-289.
[14]	Nishida T, Shimokawa H, Oi K, et al.Extracorporeal cardiac shock wave therapy markedly ameliorates ischemia-induced myocardial dysfunction in pigs in vivo[J].Circulation, 2004, 110(19):3055-3061.
[15]	Yip HK, Chang LT, Sun CK, et al.Shock wave therapy applied to rat bone marrow-derived mononuclear cells enhances formation of cells stained positive for CD31 and vascular endothelial growth factor[J].Circ J, 2008, 72(1):150-156.
[16]	Nurzynska D, Di Meglio F, Castaldo C, et al.Shock waves activate in vitro cultured progenitors and precursors of cardiac cell lineages from the human heart[J].Ultrasound Med Biol, 2008, 34(2):334-342.
[17]	Vasa M, Fichtlscherer S, Aicher A, et al.Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease[J].Circ Res, 2001, 89(1):E1-7.
[18]	Hill JM, Zalos G, Halcox JP, et al.Circulating endothelial progenitor cells, vascular function, and cardiovascular risk[J].N Engl J Med, 2003, 348(7):593-600.
[19]	Schmidt-Lucke C, Rössig L, Fichtlscherer S, et al.Reduced number of circulating endothelial progenitor cells predicts future cardiovascular events:proof of concept for the clinical importance of endogenous vascular repair[J].Circulation, 2005, 111(22):2981-2987.
[20]	Cai HY, Li L, Guo T, et al.Cardiac shockwave therapy improves myocardial function in patients with refractory coronary artery disease by promoting VEGF and IL-8 secretion to mediate the proliferation of endothelial progenitor cells[J].Exp Ther Med, 2015, 10(6):2410-2416.
[21]	Wang W, Liu H, Song M, et al.Clinical Effect of Cardiac Shock Wave Therapy on Myocardial Ischemia in Patients With Ischemic Heart Failure[J].J Cardiovasc Pharmacol Ther, 2016, 21(4):381-387.
[22]	Yu W, Shen T, Liu B, et al.Cardiac shock wave therapy attenuates H9c2 myoblast apoptosis by activating the AKT signal pathway[J].Cell Physiol Biochem, 2014, 33(5):1293-1303.
[23]	Gottlieb RA, Mentzer RM.Autophagy during cardiac stress:joys and frustrations of autophagy[J].Annu Rev Physiol, 2010, 72:45-59.
[24]	Ma X, Liu H, Foyil SR, et al.Impaired autophagosome clearance contributes to cardiomyocyte death in ischemia/reperfusion injury[J].Circulation, 2012, 125(25):3170-3181.
[25]	Matsui Y, Takagi H, Qu X, et al.Distinct roles of autophagy in the heart during ischemia and reperfusion:roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy[J].Circ Res, 2007, 100(6):914-922.
[26]	Zhang J, He Z, Xiao W, et al.Overexpression of BAG3 Attenuates Hypoxia-Induced Cardiomyocyte Apoptosis by Inducing Autophagy[J].Cell Physiol Biochem, 2016, 39(2):491-500.
[27]	Du L, Shen T, Liu B, et al.Shock Wave Therapy Promotes Cardiomyocyte Autophagy and Survival during Hypoxia[J].Cell Physiol Biochem, 2017, 42(2):673-684.
[28]	Fukumoto Y, Ito A, Uwatoku T, et al.Extracorporeal cardiac shock wave therapy ameliorates myocardial ischemia in patients with severe coronary artery disease[J].Coron Artery Dis, 2006, 17(1):63-70.
[29]	Kikuchi Y, Ito K, Ito Y, et al.Double-blind and placebo-controlled study of the effectiveness and safety of extracorporeal cardiac shock wave therapy for severe angina pectoris[J].Circ J, 2010, 74(3):589-591.
[30]	Wang Y, Guo T, Ma TK, et al.A modified regimen of extracorporeal cardiac shock wave therapy for treatment of coronary artery disease[J].Cardiovasc Ultrasound, 2012, 10:35.
[31]	刘保逸, 李文婵, 张瑞生, 等.体外心脏震波治疗老年冠心病患者的疗效和安全性分析[J].中华老年医学杂志, 2015, 34(7):736-740.
[32]	Nirala S, Wang Y, Peng YZ, et al.Cardiac shock wave therapy shows better outcomes in the coronary artery disease patients in a long term[J].Eur Rev Med Pharmacol Sci, 2016, 20(2):330-338.
[33]	Jargin SV.Shock wave therapy of ischemic heart disease in the light of general pathology[J].Int J Cardiol, 2010, 144(1):116-117.
[34]	Di Meglio F, Nurzynska D, Castaldo C, et al.Cardiac shock wave therapy:assessment of safety and new insights into mechanisms of tissue regeneration[J].J Cell Mol Med, 2012, 16(4):936-942.
[35]	Liu B, Zhang Y, Jia N, et al.Study of the Safety of Extracorporeal Cardiac Shock Wave Therapy:Observation of the Ultrastructures in Myocardial Cells by Transmission Electron Microscopy[J].J Cardiovasc Pharmacol Ther, 2018, 23(1):79-88.
[36]	宋孟仙, 刘华, 王雯霞, 等.体外心脏震波治疗对缺血性心力衰竭患者的疗效及其机制研究[J].临床心血管病杂志, 2016, 32(9):938-942.