The influence of left atrial structure and function after radiofrequency ablation of frequency prematuer contractions in different origins
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摘要: 目的:通过对比不同起源部位频发室性期前收缩 (室早) 射频消融术前及术后左心房结构及功能, 了解不同起源部位频发室早射频消融术对左心房的影响。方法:顺序收集2014-12-2017-09于我院住院, 动态心电图示室早负荷>10 000次/24h, 且成功行射频消融术患者123例。依据术中定位室早来源, 分为右室流出道游离壁24例, 右室流出道间隔部36例, 主动脉窦上36例, 主动脉窦下27例。入选患者应用心脏超声二维斑点追踪技术观察左心房结构及功能指标。结果: (1) 右室流出道游离壁来源组左心房直径 (LAD) 术前与对照组比较无显著差异;右室流出道间隔部、主动脉窦上、主动脉窦下来源组LAD术前较对照组显著增大。组间比较4组患者术后2周LAD下降至最低点, 以右室流出道间隔部减小最显著, 后依次为游离壁、主动脉窦上、主动脉窦下来源。 (2) 4组不同来源组左心房应变术前较对照组均显著降低;组间比较术后1个月左心房应变呈缓慢升高趋势并于术后1个月达最高点, 以右室流出道间隔部升高最显著, 后依次为游离壁、主动脉窦上、主动脉窦下来源。结论:频发室早可致LAD显著增大, 左心房应变显著降低, 经射频消融术后2周及1个月可逐渐改善, 尤以右室流出道间隔部改善最为显著, 后依次为游离壁、主动脉窦上、主动脉窦下来源。提示射频消融术对右室流出道间隔部、游离壁来源室早的治疗效果优于主动脉窦上及主动脉窦下来源。Abstract: Objective:To compare the structure and function of left atrium before and after radiofrequency ablation in different origin sites.Method:There were 123 hospitalized patients with PVCs observed on 24-hour Holter monitoring (>10 000/24 h) in radiofrequency ablation surgery from December 2014 to September 2017.Among them 24 patients with PVCs originating in the free wall of the right ventricular outflow tract (age:43±18 years, 10 males) , 36 in the septum of the right ventricular out flow tract (age:44±11 years, 30 males) , 36 in the above-aortic sinus (age:43±15 years, 26 males) , 27 in the below-aortic sinus (age:47±12 years, 19 males) .The indices of left atrial structure and function were measured be echocardiography before and after radiofrequency ablation surgery at1 day, 2 weeks and 1 month.Result:LAD in the right ventricular outflow tract septum, superior aortic sinus and subaortic sinus origin group were significantly larger than that in the control group (33.7±3.7, 34.1±4.3, 35.1±4.8 vs 31.5±3.9, P<0.05) .The free wall of right ventricular outflow tract, septum, superior aortic sinus and subaortic sinus S were significantly lower before operation than in control group (37.2±17.7, 39.2±16.3, 32.4±17.9, 39.8±15.3 vs 52.1±17.8, P<0.05) .Conclusion:There was a significant increase in the diameter of the left atrium and a significant decrease in the left atrial strain, 2 and 4 weeks after radiofrequency ablation, especially in the septum of the right ventricular outflow tract, followed by the right ventricular outflow tract free wall, the aortic sinus and the aortic sinus.The results suggest that radiofrequency ablation is more effective in the treatment of septum of right ventricular outflow tract than that of superior aortic sinus or subaortic sinus.
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[1] Huizar JF, Kaszala K, Potfay J, et al.Left ventricular systolic dysfunction induced by ventricular ectopy:a novel model for premature ventricular contraction-induced cardiomyopathy[J].Circ Arrhythm Electrophysiol, 2011, 4 (4):543-549.
[2] Yarlagadda RK, Iwai S, Stein KM, et al.Reversal of cardiomyopathy in patients with repetitive monomorphic ventricular ectopy originating from the right ventricular outflow tract[J].Circulation, 2005, 112 (8):1092-1097.
[3] Bogun F, Crawford T, Reich S, et al.Radiofrequency ablation of frequent, idiopathic premature ventricular complexes:Comparison with a control group without intervention[J].Heart Rhythm, 2007, 4 (7):863-867.
[4] Park Y, Kim S, Shin J, et al.Frequent premature ventricular complex is associated with left atrial enlargement in patients with normal left ventricular ejection fraction[J].Pacing Clin Electrophysiol, 2014, 37 (11):1455-1461.
[5] 陈芳, 周纪宁, 裴大军, 等.射频消融治疗频发室性期前收缩的随访研究[J].临床心血管病杂志, 2008, 24 (6):416-417.
[6] Kadri M, Yokokawa M, Labounty T, et al.Effect of ablation of frequent premature ventricular complexes on left ventricular function in patients with nonischemic cardiomyopathy[J].Heart Rhythm, 2015, 12 (4):706-713.
[7] 李赐恩, 宋卫峰, 王徐乐.导管消融术后早期左室射血分数的恢复对室性期前收缩心肌病远期预后的预测价值[J].临床心血管病杂志, 2017, 33 (8):782-785.
[8] Akkaya M, Roukoz H, Adabag S, et al.Improvement of left ventricular diastolic function and left atrial reverse remodeling after catheter ablation of premature ventricular complexes[J].Interv Card Electrophysiol, 2013, 38 (3):179-185.
[9] Zhang Y, Xie RQ, Bai H, et al.Changes of left atrial function after radiofrequency ablation of frequent premature ventricular contractions in different origins[J].Cardiac Arrhyth, 2017, 20 (3):213-218.
[10] Proclemer A, Dagres N, Marinskis G, et al.Current practice in Europe:how do we manage patients with ventricular tachycardia?European Heart Rhythm Association survey[J].Europace, 2013, 15 (2):167-169.
[11] Prystowsky EN, Padanilam BJ, Joshi S, et al.Ventricular arrhythmias in the absence of structural heart disease[J].JACC, 2012, 59 (20):1733-1744.
[12] Shvilkin A, Anter E.Cardiomyopathy-inducing premature ventricular contractions:not all animals are equal?[J].Heart Rhythm, 2012, 9 (9):1473-1474.
[13] Dukes JW, Dewland TA, Vittinghoff E et al.Ventricular ectopy as a predictor of heart failure and death[J].JACC, 2015, 66 (2):101-109.
[14] 曹锐红, 李献良.功能性室性期前收缩与左心结构及功能的相关性[J].临床心血管病杂志, 2015, 31 (9):965-968.
[15] Zang M, Zhang T, Mao JL, et al.Beneficial effects of catheter ablation of frequent premature ventricular complexes on left ventricular function[J].Heart, 2014, 100 (10):787-793.
[16] Del Carpio Munoz F, Syed FF, Noheria A, et al.Characteristics of premature ventricular complexes as correlates of reduced left ventricular systolic function:study of the burden, duration, coupling interval, morphology, and site of origin of PVCs[J].J Cardiovasc Electrophysiol, 2011, 22 (7):791-798.
[17] Fichtner S, Senges J, Hochadel M, et al.Safety and efficacy in ablation of premature ventricular contraction:data from the German ablation registry[J].Clin Res Cardiol, 2017, 106 (1):49-57.
[18] Chen T, Koene R, Benditt DG, et al.Ventricular ectopy in patients with left ventricular dysfunction:should it be treated?[J].Card Fail, 2013, 19 (1):40-49.
[19] Del Carpio Munoz F, Syed FF, Noheria A, et al.Characteristcs of premature ventricular complexes as correlates of reduced left ventricular systolic function:study of the burden, duration, coupling interval, morphology and site of origin of PVCs[J].Cardiovasc Electrophysiol, 2011, 22 (7):791-798.
[20] Ma YM, Shi XM, Chen Q, et al.HRV changes before and after Radiofrequency Ablation in Patients with Different Origin of Right Ventricular Outflow Tract Ventricular Premature Contraction[J].Hai Nan Medical College Newspaper, 2016, 20:200-212.
[21] Badran H, Samir R, Amin M, et al.Outflow tract ventricular premature beats ablation in the presence or absence of structural heart disease:Technical considerations and clinical outcomes[J].Egypt Heart J, 2017, 69 (4):273-280.
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