Clinical features and risk factors of coronary heart disease with chronic kidney disease
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摘要: 目的:评价在冠心病(CHD)患者中慢性肾脏病(CKD)的患病情况及影响因素。方法:就诊于河南省人民医院的确诊CHD的患者507例,根据CKD的诊断标准分为CKD组135例和非CKD组372例,分析CHD患者中CKD的患病情况及影响因素。结果:CHD患者中的CKD的患病率为26.6%。CKD组患者高血压、糖尿病患病率、低密度脂蛋白胆固醇(LDL-C)、空腹血糖(FBG)、尿酸、收缩压、舒张压水平均高于非CKD组。非CKD组的372例CHD患者中,25.8%的患者不清楚自己的肾功能状况,74.2%的患者认为自己的肾功能正常。在CKD组的135例患者中,57.8%的患者不清楚自己的肾功能状况,42.2%的患者认为自己的肾功能正常。多因素logistic回归分析显示,糖尿病(OR=1.753)、高LDL-C(OR=2.108)、高尿酸(OR=1.007)是CHD患者发生CKD的危险因素。结论:CHD患者中的CKD患病率为26.6%,糖尿病、高LDL-C、高尿酸是CHD患者发生CKD的危险因素。Abstract: Objective:To evaluate the prevalence and risk factors of coronary heart disease(CHD) with chronic kidney disease(CKD).Method:A total of 507 patients with confirmed CHD were enrolled in the Henan Provincial People's Hospital.According to the diagnostic criteria of CKD,135 patients in the CKD group and 372 patients in the non-CKD group were analyzed.The prevalence and risk factors of CHD with CKD were analyzed.Result:The prevalence of CKD in CHD patients was 26.6%.Hypertension,diabetes,low-density lipoprotein cholesterol(LDL-C),fasting blood glucose(FBG),uric acid,systolic blood pressure(SBP),diastolic blood pressure(DBP) level in the CKD group was higher than those of the non-CKD group.In the non-CKD group,25.8% were unclear about their renal function,and 74.2% thought their kidney function was normal.In the CKD group,57.8% were unclear about their renal function,and 42.2% thought their kidney function was normal.Multivariate logistic regression analysis showed that diabetes(OR=1.753),high LDL-C(OR=2.108),and high uric acid(OR=1.007)were risk factors for CHD with CKD.Conclusion:The prevalence of CKD in CHD patients is 26.6%.Diabetes,high LDL-C and high uric acid are risk factors for CHD with CKD.
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Key words:
- coronary heart disease /
- chronic kidney disease
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