Protein losing enteropathy-neglected in the diagnosis and treatment of cardiovascular diseases
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摘要: 蛋白丢失性肠病(PLE)是由多种原发性疾病导致大量蛋白质从肠道丢失的临床综合征,最常继发于胃肠道疾病和心血管疾病。PLE的发生发展与心血管原发疾病密切相关,PLE目前在心血管领域整体认识度较低,未能及时诊断PLE,导致持续或难以纠正的低蛋白血症,原发疾病也可能随PLE的发展而逐渐复杂化,从而严重影响患者的生存质量和预后。本文详述了心血管疾病相关PLE的发病特点和机制,以及诊断和治疗,以期提高PLE的知晓率、诊断率和治疗率,改善患者的生活质量和预后。Abstract: Protein losing enteropathy(PLE) is a clinical syndrome in which a large amount of proteins is lost from the intestine due to a variety of primary diseases, most often secondary to gastrointestinal and cardiovascular disease. The occurrence and development of PLE are closely related to the primary cardiovascular diseases. The overall awareness of PLE in cardiovascular field is low currently. The failure to diagnose of PLE in time leads to persistent or uncorrectable hypoproteinemia. The primary disease may also be complicated by the progress of PLE, which seriously affects the life quality and prognosis of patients. This article details the characteristics and pathogenesis of cardiovascular disease-related PLE, as well as diagnosis and treatment, in order to raise the awareness, diagnosis rate and treatment rate of PLE, and improve the life quality and prognosis of patients.
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Key words:
- protein losing enteropathy /
- cardiovascular disease /
- diagnosis /
- treatment
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