新生儿持续性肺动脉高压与先天性心脏病相关肺动脉高压导致心脏损伤的比较研究

张雅芝; 彭华; 刘亚兰; 王秋鹏; 陈燕; 刘亚玲

doi:10.13201/j.issn.1001-1439.2021.06.014

新生儿持续性肺动脉高压与先天性心脏病相关肺动脉高压导致心脏损伤的比较研究

- 华中科技大学同济医学院附属协和医院儿科(武汉,430022)

详细信息

通讯作者: 刘亚玲,E-mail:lyl_uh2020@126.com

中图分类号: R541

收稿日期: 2020-04-01

Comparison of cardiac injury caused by persistent pulmonary hypertension and congenital heart disease-related pulmonary hypertension in the newborn

- Department of Paediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China

More Information

Corresponding author: LIU Yaling, E-mail: lyl_uh2020@126.com

Received Date: 01 April 2020

摘要

摘要: 目的:探讨新生儿持续性肺动脉高压(PPHN)与先天性心脏病相关肺动脉高压(PAH-CHD)在导致患儿心脏损伤方面的差异。方法:回顾性分析我院新生儿病房2014年11月—2020年6月收治的符合肺动脉高压的患儿161例,分为PPHN组与PAH-CHD组。比较两组患儿心脏超声指标与心肌酶的差异。结果:PAH-CHD组与PPHN组左房内径(LA)、左室内径(LV)及左室射血分数(LVEF)的差异具有统计学意义(P<0.05);其他指标如右房内径(RA)、右室内径(RV)及心肌酶在两组之间差异无统计学意义。结论:对比PPHN患儿,PAH-CHD更容易引起LV、LA及LVEF改变,临床需要尽早识别,进行干预。
- 新生儿 /
- 肺动脉高压 /
- 先天性心脏病
Abstract: Objective: To investigate the difference of cardiac injury between persistent pulmonary hypertension(PPHN) and congenital heart disease-related pulmonary hypertension(PAH-CHD) in neonatus.Methods: A total of 161 children with pulmonary hypertension in neonatal intensive care unit of our hospital from November 2014 to June 2020 were retrospectively included and divided into PPHN group and PAH-CHD group. The differences of echocardiography indicators and myocardial enzyme levels between the two groups were compared.Results: There were significant differences in left atrial diameter(LA), left ventricular diameter(LV), and left ventricular ejection fraction(LVEF) between PAH-CHD group and PPHN group(all P<0.05). There was no significant difference in other indexes such as right atrial diameter(RA), right ventricular diameter(RV), and myocardial enzymes between the two groups.Conclusion: Compared with PPHN, PAH-CHD is more likely to cause changes in cardiac structure and ejection fraction. In order to intervene, early identification is particularly necessary in clinic.
- neonatus /
- pulmonary hypertension /
- congenital heart disease

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参考文献(14)

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