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摘要: 冠状动脉功能学评估是经皮冠状动脉介入治疗(PCI)临床决策的主要依据。血流储备分数(FFR)是功能学评估的金标准，但限于操作复杂、耗时长等原因，其临床应用十分有限。随着计算流体力学的发展，基于影像衍生的功能学指标(CT-FFR、QFR、caFFR、caIMR等)应运而生，其无创、高效且诊断准确率较高，在介入术前评估和术中指导中逐渐体现出优势。本文将介绍不同功能学衍生技术的应用场景，并对影像与功能学联合应用的价值进行展望。Abstract: Coronary function assessment has become the cornerstone of clinical decision-making in percutaneous coronary intervention(PCI). Fractional flow reserve(FFR) is the gold standard for functional assessment, but its clinical application is limited due to the complicated and time-consuming procedure. With the development of computational fluid dynamics technology, imaging-derived functional indicators(CT-FFR, QFR, caFFR, caIMR, etc.) have emerged, which are non-invasive, efficient and have high diagnostic accuracy, and have advantages in pre-assessment and guidance of PCI. This article will introduce the application scenarios of different functional derived techniques, and discuss the value of the combined use of imaging and functional techniques.
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Key words:
- coronary artery disease /
- fractional flow reserve /
- CT-FFR /
- QFR /
- caFFR /
- caIMR
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