Research progress of CTRP9 and type 2 diabetes mellitus associated with atherosclerosis
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摘要: 冠心病是2型糖尿病的主要并发症，也是2型糖尿病患者死亡的重要原因，延缓2型糖尿病患者动脉粥样硬化的进展成为提高人类生活质量的紧迫问题。C1q肿瘤坏死因子相关蛋白9(CTRP9)作为心血管保护因子，在延缓2型糖尿病相关动脉粥样硬化的进展中发挥什么作用，是目前学术界研究的热点。本综述总结了CTRP9在2型糖尿病相关动脉粥样硬化中作用的最新进展，重点介绍其在2型糖尿病相关动脉粥样硬中的作用机制，为预防及治疗糖尿病相关动脉粥样硬化提供新的思路及解决方法。Abstract: Coronary atherosclerotic heart disease is not only a major complication of type 2 diabetes mellitus but also an important cause of death in patients with this condition. Delaying the progress of atherosclerosis in patients with type 2 diabetes mellitus has become an urgent issue to improve human life quality. Accumulated evidence suggests that C1q tumor necrosis factor-related protein 9 (CTRP9) could play a role in preventing the progression of type 2 diabetes-related atherosclerosis. In this review, we summarize the latest progress in the role of CTRP9 in type 2 diabetes-related atherosclerosis, focusing on its mechanism in type 2 diabetes-related atherosclerosis to provide new ideas and solutions for the prevention and treatment of diabetes-related atherosclerosis.
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Key words:
- CTRP9 /
- type 2 diabetes mellitus /
- atherosclerosis
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