Tp-ec、Tp-e/QT对急性ST段抬高性心肌梗死恶性心电生理事件的预测价值

肖国胜; 王宪沛; 高传玉; 王焱; 刘静静

doi:10.13201/j.issn.1001-1439.2012.07.012

Tp-ec、Tp-e/QT对急性ST段抬高性心肌梗死恶性心电生理事件的预测价值

- 1. 厦门大学附属中山医院心脏中心(厦门, 361004);
- 2. 河南省人民医院心内科河南省心血管流行病学研究所

详细信息

通讯作者: 王焱,E-mail:dugusiliang@163.com

中图分类号: R542.2

收稿日期: 2011-11-21

Predictive value of Tp-ec and Tp-e/QT on occurrence of malignant cardiac electrophysiological events in patients with acute ST segment elevation myocardial infarction

- 1. Department of Cardiology, Zhongshan Hospital, Xiamen University, Xiamen, 361004, China;
- 2. Department of Cardiology, Henan Provincial People's Hospital, Institute of Cardiovascular Epidemiology of Henan Province

More Information

Corresponding author: WANG Yan, E-mail: dugusiliang@163.com

Received Date: 21 November 2011

摘要

摘要: 目的:观察急性ST段抬高性心肌梗死(STEMI)患者QT间期、Tp-ec(校正的T波的顶点到T波的终点的时间)和Tp-e/QT指标的变化及这些指标与恶性心电生理事件的相关性。方法:急性STEMI患者60例,测量并计算梗死相关和非梗死导联QT、QTc、Tp-ec、Tp-e/QT比值,记录1年内恶性心电生理事件。正常心电图60例作为对照。结果:①急性STEMI 12h内梗死和非梗死导联QTc明显延长(P<0.01),1周和1个月回复正常水平。梗死相关导联12h内Tp-ec间期比非梗死导联及对照组均明显延长(均P<0.01),1周和1个月逐渐回复正常。Tp-e/QT比值在梗死相关导联比其他导联明显增大(P<0.01),随之逐渐回复,但仍与对照组差异有统计学意义(P<0.01)。②QTc 440ms作为截点电生理事件发生差异无统计学意义(P>0.05),而分别以Tp-ec100ms和Tp-e/QT比值0.25作为截点恶性电生理事件发生差异有统计学意义(P<0.05)。结论:在心肌梗死急性期Tp-ec,尤其是Tp-e/QT比值增加,与恶性电生理事件相关,是预测急性STEMI后恶性电生理事件的指标。
- 心肌梗死 /
- Tp-e间期 /
- Tp-e/QT比值 /
- 跨室壁离散 /
- 恶性电生理事件
Abstract: Objective:To predict the value of Tp-ec(corrected Tp-e) and Tp-e/QT on occurrence of malignant cardiac electrophysiological events(MCEE) in acute ST segment elevation myocardial infarction(STEMI) patients. Method:Different indices of QT,QTc,Tp-ec,Tp-e/QT were measured and calculated in infarction-related ECG lead and non-infarction-related lead,respectively,in clinical definited 60 cases of STEMI patients.MCEE were recorded in one year.Sixty cases of normal patients ECG were aollected as control group. Result:①QTc of infarction-related lead and non-infarction-related lead were prolonged significantly in 12 hours after acute STEMI(P<0.01),and then returned to normal level in one week and one month,respectively(P<0.01).Comparing(QTc,QT Tp-ec,Tp-e/QT) in non-infarction-related lead and control,Tp-ec intervals in infarction-related lead were prolonged significantly,and recovered gradually(P<0.01) to the level which was no difference with that of control in one week and one month(P>0.05).While Tp-e/QT ratio in infarction-related lead increased significantly compared with those in other group,then recovered,the recovered value still had significant difference with that in control(P<0.05).②The occurrence of MCEE had no difference between QTc joint points as 440 ms(P>0.05).And the occurrence of MCEE had significant difference(P<0.05) when joint point of Tp-ec as 100 ms and that of Tp-e/QT ratio as 0.25,respectively. Conclusion:In the acute phase of myocardial infarction,the increase of Tp-ec,and specially Tp-e/QT ratio are correlated with occurrence of MCEE.Tp-ec and Tp-e/QT are indicators to predict MCEE in acute STEMI patients.
- myocardial infarction /
- Tp-e interval /
- Tp-e/QT ratio /
- transmural dispersion /
- malignant cardiac electrophysiological events

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