Red cell distribution width predicts poor myocardial perfusion in patients with acute inferior myocardial infarction treated with primary percutaneous coronary intervention
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摘要: 目的：探讨红细胞分布宽度（RDW）对接受直接经皮冠状动脉介入治疗（PCI）的急性下壁心肌梗死患者心肌灌注不良的预测价值。方法：201例因急性下壁心肌梗死入院行PCI的患者，根据入院时RDW中位数（13.0%）分为RDW≤13.0%组（110例）和RDW>13.0%组（91例）。对2组患者的一般临床资料、心脏超声和急诊PCI术后心电图单导联ST段回落率（STR）进行分析，并对相关数据进行Logistic回归分析。结果：与RDW≤13.0%组比较，RDW>13.0%组PCI术后STR>50%的比例（52.75%：72.73%）和左室射血分数[（50.54±5.59）%：（52.39±6.12）%]均显著降低（均P<0.05）。Logistic回归分析显示，入院时RDW水平与STR峰值呈显著负相关（r=-0.282，P=0.001）。结论：入院时RDW水平升高是急性下壁心肌梗死患者心肌灌注不良的独立预测指标。
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关键词:
- 心肌梗死 /
- 血管成形术,经腔,经皮冠状动脉 /
- 红细胞分布宽度 /
- 心肌再灌注
Abstract: Objective: To evaluate the predictive value of red cell distribution width(RDW) on the development of poor myocardial perfusion in patients with acute inferior myocardial infarction treated with primary percutaneous coronary intervention(PCI). Method: A total of 201 patients with acute inferior myocardial infarction received primary PCI.According to the level of median RDW on admission, they were divided into RDW ≤ 13.0% group(n=110) and RDW>13.0% group(n=91).Clinical characteristics, echocardiography and single lead of ST-segment resolution rate(STR) after PCI were recorded and analyzed prospectively. Result: Compared with RDW ≤ 13.0% group, the proportion of STR>50%(52.75% vs 72.73%) and left ventricular ejection fractions[(50.54±5.59)% vs(52.39±6.12)%] were significantly decreased in RDW>13.0% group(both P<0.05).Logistic regression analysis showed that admission RDW level was negatively correlated with STR(r=-0.282, P=0.001). Conclusion: A high baseline RDW value is independently associated with the presence of electrocardiographic no-reflow in patients with acute inferior myocardial infarction. -
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