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摘要: 组织蛋白酶L (cathepsin L) 是半胱氨酸组蛋白酶家族中的细胞内高效蛋白酶之一, 在部分血管疾病、心脏扩大发生以及冠心病预测等方面发挥了重要作用。因此, 明确组织蛋白酶L在心血管系统中的作用, 对心血管疾病的诊断和治疗有着重要意义。本文对组织蛋白酶L对心血管影响的研究现状做一综述。Abstract: Cathepsin L is an intracellular protease with high potency, which belongs to cysteine cathepsin family.It plays an important role in the pathogenesis of part of vascular diseases, cardiac dilation and prognosis of coronary heart disease.Elucidating the role of cathepsin L in cardiovascular diseases is crucial to the diagnosis and treatment.This review summarizes the current researches about the effects of cathepsin L on cardiovascular system.
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Key words:
- coronary disease /
- cathepsin L /
- atherosclerosis /
- angiogenesis /
- dilated heart
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