预防性主动脉球囊反搏术用于高危PCI术疗效的Meta分析

万成; 蒋学俊; 杨汉东

doi:10.13201/j.issn.1001-1439.2014.07.011

预防性主动脉球囊反搏术用于高危PCI术疗效的Meta分析

- 1 武汉大学人民医院心内科一病区(武汉, 430060);
- 2 湖北医药学院附属东风总医院心血管内科 (湖北十堰, 442000)
基金项目:
湖北省自然科学基金项目 (No:2012FFA052)

湖北省高等学校优秀中青年团队计划项目 (No:T201212)

详细信息

通讯作者: 杨汉东,E-mail:yanghand@139.com

中图分类号: R541.4

收稿日期: 2013-11-23

Efficacy of IABP on the high-risk PCI:a systematic review-meta analysis

- 1 Department of Cardiology, Renmin Hospital Affiliated to Wuhan University, Wuhan, 430060, China;
- 2 Department of Cardiology, Dongfeng Motor General Hospital Affiliated to Hubei University of Medicine, Shiyan, 442000, China

More Information

Corresponding author: YANG Handong, E-mail: yanghand@139.com

Received Date: 23 November 2013

摘要

摘要: 目的:系统评价预防性主动脉球囊反搏术 (prophylactic intra-aortic balloon pump, P-IABP) 对高危PCI术患者 (high-risk percutaneous coronary intervention, HR-PCI) 的疗效, 反映P-IABP用于HR-PCI的治疗现状。方法:在数据库中以HR-PCI为研究对象, 进行P-IABP联合PCI治疗 (治疗组) 与单独PCI术治疗 (对照组) 比较的随机对照试验 (RCT), 对短期和长期死亡率及主要心脑血管不良事件 (MACCE) 进行Meta分析。结果:共纳入8篇RCT, 包括1634例患者。经Meta分析, P-IABP用于HR-PCI并不能显著降低患者的短期死亡率[1.09, 95%CI (0.68, 1.78), P=0.73]和MACCE发生率[0.90, 95%CI (0.66, 1.23), P=0.51], 但P-IABP组的远期死亡率相比对照组显著降低[0.63, 95%CI (0.45, 0.89), P=0.009]。结论:现有证据表明P-IABP并不能显著降低HR-PCI患者的短期死亡率和MACCE, 但能降低其远期死亡率。
- 主动脉内球囊反搏术 /
- 高危冠脉介入 /
- 随机对照试验 /
- 系统评价 /
- Meta分析
Abstract: Objective: To systematically evaluate the effectiveness of prophylactic intra-aortic balloon pump (PIABP) on patients undergoing high-risk percutaneous coronary intervention (PCI).Method: Randomized-Controlled Trials (RCTs) comparing the impact of P-IABP on patients undergoing HR-PCI with that of HR-PCI alone were included to evaluate the effectiveness of P-IABP on HR-PCI in a method of Meta-analysis.Result: Totally 8RCTs were identified including 1634 patients.Meta-analysis figure out that compared with control group the short-term mortality[1.09, 95%CI (0.68, 1.78), P=0.73]and MACCE[0.90, 95%CI (0.66, 1.23), P=0.51]of P-IABP group was not significantly reduced.In contrast, the long-term mortality showed a significant reduction[0.63, 95%CI (0.46, 0.87), P=0.006].Conclusion: These included researches demonstrated that PIABP can not improve the short-term outcomes including the occurrence of MACCE after HR-PCI, but it did reduce the long-term mortality.
- intra-aortic balloon pump /
- high risk percutaneous coronary intervention /
- randomized controlled trials /
- systematic review /
- meta-analysis

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