血浆脑钠肽在非ST段抬高急性冠状动脉综合征危险分层中的临床意义

江荣炎; 蒋爱清

doi:10.13201/j.issn.1001-1439.2015.05.019

血浆脑钠肽在非ST段抬高急性冠状动脉综合征危险分层中的临床意义

- 亳州市人民医院心内科(安徽亳州, 236800)

详细信息

作者简介:
江荣炎,E-mail:jiangshamr@sina.com

中图分类号: R541.4

收稿日期: 2014-09-28

The clinical value of N-terminal natriuretic peptide in risk stratification for the patients with non-ST elevation acute coronary syndrome

- Department of Cardiology, Bozhou People's Hospital, Bozhou, Anhui, 236800, China

Received Date: 28 September 2014

摘要

摘要: 目的:探讨非ST段抬高急性冠状动脉综合征(NSTE-ACS)患者血中N末端脑钠肽(NT-BNP)水平在危险分层中的意义。方法:入选81例患者,入院检查NT-BNP及肌钙蛋白I浓度(cTnI),依据GRACE评分标准对患者进行风险评估,计算积分,并进行危险分层,分为低危、中危、高危3组。分析NT-BNP与cTnI浓度及GRACE积分的关系;对比不同组别患者NT-BNP水平的差异。结果:NSTE-ACS患者NT-BNP与cTnI及GRACE积分呈正相关,并且低危、中危及高危组之间NT-BNP浓度有显著性差异(P<0.05)。结论:NSTE-ACS患者NT-BNP水平越高,GRACE积分越高,NT-BNP的检测对NSTE-ACS患者进行早期、快速的危险度分层方面有着独特的价值。
- N端脑钠肽 /
- 非ST段抬高急性冠脉综合征 /
- GRACE评分
Abstract: Objective:To explore the clinical value of N-terminal natriuretic peptide(NT-BNP) in risk stratification for patients with non-ST elevation acute coronary syndrome(NSTE-ACS).Method:We enrolled 81 patients with NSTE-ACS.In these patients,NT-BNP and cardiac troponin I(cTnI) concentration were tested.According to the GRACE score standard,all patients were stratified into threee groups.The relationship between NT-BNP level and GRACE risk score as well as cTn I was analyzed.The difference of NT-BNP in three groups was compared.Result:The relationship between NT-BNP level and GRACE score as well as cTnI were positively correlated.The NT-BNP levels in three groups had significant differences(P<0.05).Conclusion:In patients with NSTE-ACS,the higher NT-BNP concentration,the higher the GRACE scoreis.Measurement of NT-BNP is valuable for risk stratification in patients with NSTE-ACS.
- N-terminal brain natriuretic peptide /
- acute coronary syndrome /
- GRACE score

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