动脉粥样硬化患者动脉硬化程度与淋巴细胞、中性粒细胞的相关性研究

王欢; 胡元会; 魏艺; 李可; 杜柏

doi:10.13201/j.issn.1001-1439.2015.12.013

动脉粥样硬化患者动脉硬化程度与淋巴细胞、中性粒细胞的相关性研究

- 1 中国中医科学院广安门医院(北京, 100053);
- 2 中国中医科学院在读博士研究生;
- 3 北京中医药大学在读硕士研究生

详细信息

通讯作者: 胡元会,E-mail:huiyuhui55@sohu.com

中图分类号: R543

收稿日期: 2015-03-16

The relationship between the degree of arteriosclerosis and the level of lymphocytes,neutrophils in patients with arteriosclerosis

- 1 Guang'anmen Hospital, China Academy of Chinese Medical Science, Beijing, 100053, China;
- 2 China Academy of Chinese Medical Science;
- 3 Beijing University of Chinese Medicine

More Information

Corresponding author: HU Yuanhui, E-mail: huiyuhui55@sohu.com

Received Date: 16 March 2015

摘要

摘要: 目的:研究体检人群动脉弹性与淋巴细胞、中性粒细胞的关系。方法:选择体检者304例,询问病史、测量身高、体重、BMI、血压等,检测血常规、生化等指标,应用欧姆龙BP-203RPEⅢ动脉硬化检测仪检测体检人群的动脉弹性,根据脉搏波传导速度(baPWV)分为动脉正常组(117人)、轻度硬化组(112人)与硬化组(75人),比较3组之间的白细胞水平。结果:轻度硬化组、硬化组中性粒细胞百分比(NEU)均较正常组升高(均P＜0.01),淋巴细胞百分比(LYM)均较正常组降低(均P＜0.01)。相关性分析显示,NEU、中性粒细胞与淋巴细胞比值(NLR)与baPWV呈正相关(r=0.30、033,均P<0.05),LYM与baPWV呈负相关(r=-0.32,P<0.05)。结论:NEU、LYM、NLR是评价心血管危险程度的重要指标,应加强对动脉硬化人群炎症反应的检测,及时调整炎症/免疫状态,抑制动脉粥样硬化的发生发展,减少心血管疾病的发生。
- 动脉弹性 /
- 中性粒细胞百分比 /
- 淋巴细胞百分比 /
- 中性粒细胞与淋巴细胞的比值
Abstract: Objective: To study the relationship between arteriosclerosis and the level of neutrophil and lymphocytes. Method: Three hundred and four cases underwent physical examination were selected. The medical history, height, weight, BMI, blood pressure, blood routine and biochemical indicators were observed. Omron BP-203RPEⅢ arteriosclerosis arterial elasticity detector was applied to test arterial elasticity, and all cases were included into normal group (n=117), mild sclerosis group (n=112) and hardening group (n=75) according to baPWV. The white blood cell levels were tested and compared among the three groups.Result: Compared to normal group, NEU in mild sclerosis group and sclerosis group were significantly increased (both P<0.01), while LYM were significantly decreased (both P<0.01). Correlation analysis showed that NEU and NLR were positively correlated with baPWV respectively(r=0.30, 033,both P<0.05), and LYM was negatively correlated with baPWV(r=-0.32,P<0.05).Conclusion: NEU, LYM and NLR are important indicators of the degree of cardiovascular risk evaluation. We should strengthen the detection of atherosclerosis crowd inflammation, with timely adjustment of the inflammatory/immune status, thus inhibiting the occurrence of atherosclerosis development and reduceing the incidence of cardiovascular disease.
- arterial elasticity /
- the percentage of neutrophils /
- lymphocyte percentage /
- neutrophils and lymphocytes ratio

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