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Abstract: One case of Kounis syndrome was retrospectively analyzed, and the literatures related to this disease were searched to summarize and analyze the clinical manifestation diagnosis and treatment of this disease. Kounis syndrome is acute coronary syndrome associated with anaphylaxis, it is caused by inflammatory mediators (histamine etc.)released through master cell-degranulation, which lead to coronary artery spasm,plaque disruption and thrombus formation. The treatment of Kounis syndrome should include two parts, which are anaphylaxis and ACS.
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Key words:
- Kounis syndrome /
- acute coronary syndrome /
- anaphylaxis /
- literature review
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[1] KOUNIS N G, ZAVRAS G M. Histamine-induced coronary artery spasm:the concept of allergic angina[J]. Br J Clin Pract, 1991, 45:121-128.
[2] PFISTER C W, PLICE S G. Acute myocardial infarction during a prolonged allergic reaction to penicillin[J]. Am Heart J, 1950, 40:945-947.
[3] NIKOLAIDIS L A, KOUNIS N G, GRADMAN A H. Allergic angina and allergic myocardial infarction:a new twist on an old syndrome[J]. Can J Cardiol, 2002, 18:508-511.
[4] KOUNIS N G. Kounis syndrome (allergic angina and allergic myocardial infarction):a natural paradigm[J]. Int J Cardiol, 2006, 110:7-14.
[5] LINDSTEDT K A, KOVANEN P T. Mast cells in vulnerable coronary plaques:potential mechanisms linking mast cell activation to plaque erosion and rupture[J]. Curr Opin Lipidol, 2004, 15:567-573.
[6] 任雅琦, 王宁夫. Kounis综合征的研究进展[J]. 中华心血管病杂志, 2013, 41(6):527-529.
[7] STEFFEL J, AKHMEDOV A, GREUTERT H, et al. Histamine induces tissue factor expression:implications for acute coronary syndromes[J]. Circulation, 2005, 112(3):341-349.
[8] JOHNSON J L, JACKSON C L, ANGELINI G D, et al. Activation of matrix-degrading metalloproteinases by mast cell proteases in atherosclerotic plaques[J]. Arterioscler Thromb Vasc Biol, 1998, 18:1707-1715.
[9] BITEKER M. A new classification of Kounis syndrome[J]. Int J Cardiol, 2010, 145:553-555.
[10] DOGAN V, MERT G O, BITEKER F S, et al. Treatment of Kounis syndrome[J]. Int J Cardiol, 2015, 181:133-134.
[11] 鲁端. 过敏性心肌缺血综合征的现代认识[J]. 心电与循环, 2013, 11(4):253-256, 259.
[12] NG KOUNIS S G, TSIGKAS G G. Eosinophilic responses to stent implantation and the risk of Kounis hypersensitivity associated coronary syndrome[J]. Int J Cardiol, 2012, 181:133-134.
[13] GOMEZ C M S, CASTRO O M J, RODRIGUEZ F F J, et al. Treatment of Kounis syndrome[J]. Med Intensiva, 2011, 35(8):519-520.
[14] 范金波, 陈历水, 冯叙桥. 抗过敏功能活性成分研究进展[J]. 食品工业科技, 2013, 20(21):361-365.
[15] 李福高, 徐承智, 虞英民. 依巴斯汀临床研究进展[J]. 中国医药导刊, 2015, 10(4):371-374.
[16] 曾汇庆, 刘品明. 过敏反应相关的急性冠状动脉综合征[J]. 中华心血管病杂志, 2014, 42(5):111-115.
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