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摘要: 新型冠状病毒在国内传播流行的威胁仍然存在。新型冠状病毒肺炎(COVID-19)患者中,合并高血压的比例较高。新型冠状病毒通过与肺泡等细胞膜上的血管紧张素转换酶2(ACE2)结合进入机体,并引起后续病变,有证据显示血管紧张素转换酶抑制剂/血管紧张素受体拮抗剂(ACEI/ARB)类降压药物可以升高ACE2的表达,因此COVID-19合并高血压的患者是否应用ACEI/ARB存在一定争论。本文对应用ACEI/ARB的利弊作简要介绍。Abstract: The threat of the novel coronavirus spreading in China still exists.The proportion of hypertensive patients with novel coronavirus pneumonia(COVID-19) is relatively high.Due to the combination of the novel coronavirus with ACE2 on the alveolar membrane and causing subsequent lesions,and ACEI/ARB antihypertensive drugs can increase the expression of ACE2,so there is a certain controversy about whether to use ACEI/ARB in hypertensive patients complicated with COVID-19.In this paper,the advantages and disadvantages of ACEI/ARB will be briefly introduced.
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