冠状动脉造影和血管内影像来源血流储备分数的基本原理和研究进展

胡新央; 吴献鹏

doi:10.13201/j.issn.1001-1439.2023.10.002

冠状动脉造影和血管内影像来源血流储备分数的基本原理和研究进展

胡新央^1, ,,
吴献鹏¹

- 浙江大学医学院附属第二医院心血管内科(杭州，310009)

详细信息

通讯作者: 胡新央，E-mail：hxy0507@zju.edu.cn

中图分类号: R541.4

收稿日期: 2023-08-14

刊出日期: 2023-10-13

The basic principles and recent advancements in coronary angiography and intravascular imaging-derived fractional flow reserve

HU Xinyang^1, ,,
WU Xianpeng¹

- Department of Cardiology, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, China

More Information

Corresponding author: HU Xinyang, E-mail: hxy0507@zju.edu.cn

Received Date: 14 August 2023

Publish Date: 13 October 2023

摘要

摘要: 血流储备分数是有创评估冠状动脉缺血病变的金标准，但额外压力导丝以及充血试剂的使用，限制了其在临床中的广泛应用。近年来，基于计算生理学技术的冠状动脉造影和血管内影像来源的血流储备分数得到快速发展，能在避免压力导丝和充血试剂使用的同时，实现依据解剖学影像完成冠状动脉的功能学评估。定量血流分数、基于光学相干断层成像的血流储备分数以及基于血管内超声的血流储备分数是该领域的研究热点和前沿技术。因此，本文将对上述技术的基本原理和研究展开综述。
- 血流储备分数 /
- 定量血流分数 /
- 基于光学相干断层成像的血流储备分数 /
- 基于血管内超声的血流储备分数
Abstract: Fractional flow reserve(FFR) is the invasive gold standard for assessing coronary ischemic lesions, but its wide application in the clinic is limited due to the use of additional pressure wires and vasodilators. In recent years, the FFR derived from coronary angiography and intravascular imaging, based on computational physiology technology, has rapidly developed. It enables functional evaluation of coronary artery stenosis based on anatomical imaging, while avoiding the use of pressure guidewires and vasodilators. Notably, the quantitative flow ratio, optical coherence tomography-derived FFR, and intravascular ultrasound-derived FFR have emerged as pivotal research areas and are at the forefront of technological innovation in this domain. Therefore, this article will provide a review of the basic principles and research progress concerning above technologies.

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