Treatment strategies for patients with severe chronic thromboembolic pulmonary hypertension
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摘要: 慢性血栓栓塞性肺动脉高压(CTEPH)是一种致命性疾病,由于诊断延迟、诊断不充分等,大多数患者就诊时已达到重度肺动脉高压水平。对于这些重度肺动脉高压患者,单一治疗效果不佳,可选择将肺动脉内膜剥脱术(PEA)与球囊肺动脉成形术(BPA)、靶向药物相结合,以降低手术风险,或解决残余肺动脉高压。多种药物联合或BPA与药物组合为无法手术的CTEPH患者提供了新的治疗选择。本文旨在为重度CTEPH患者的治疗,尤其是联合治疗方案的选择提供参考。
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关键词:
- 肺动脉高压, 血栓栓塞性, 慢性 /
- 肺动脉内膜剥脱术 /
- 球囊肺动脉成形术
Abstract: Chronic thromboembolic pulmonary hypertension(CTEPH) is a fatal disease. Due to delayed diagnosis or inadequate diagnosis, most patients have reached the level of severe pulmonary hypertension at the time of diagnosis. For patients with severe pulmonary hypertension, a single treatment is not effective. Pulmonary endarterectomy(PEA) can be combined with balloon pulmonary angioplasty(BPA) or targeted drugs to reduce the risk of surgery or solve residual pulmonary hypertension. Multiple drug combinations or BPA in combination with drugs provide new treatment options for patients with inoperable CTEPH. This article aims to provide a reference for treating patients with severe CTEPH, especially the choice of combined treatment options. -
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