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摘要: 华法林在临床应用有一定局限性,需要有新的抗凝剂来代替。本文主要对新近出现的抗凝药物,如直接Xa因子抑制剂、直接凝血酶抑制剂和新型维生素K拮抗剂作一综述。Abstract: Warfarin has variable and unpredictable antithrombotic effect,and needs regular monitoring and dose adjustment.So it is necessary to investigate alternative drugs for warfarin.Some new anticoagulants including direct factor Xa inhibitors,direct thrombin inhibitors and novel vitamin K antagonist were reviewed in this article.
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Key words:
- warfarin /
- direct Xa inhibitor /
- direct thrombin inhibitor /
- vitamin K antagonist
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