肾去交感神经术治疗心力衰竭的研究进展

宋立君; 卢成志; 王丽

doi:10.13201/j.issn.1001-1439.2015.05.004

肾去交感神经术治疗心力衰竭的研究进展

- 1 天津医科大学一中心临床学院(天津, 300192);
- 2 天津市第一中心医院心内科
基金项目:
天津市应用基础与前沿技术研究计划(No:14JCYBJC26100)

天津市卫生局科技基金(No:2014KY11)

详细信息

作者简介:
卢成志,E-mail:lucz8@126.com

中图分类号: R541.6

收稿日期: 2015-01-10

Research progress of renal denervation in treatment of heart failure

- 1 The First Center of Clinical College, Tianjin Medical University, Tianjin, 300192, China;
- 2 Department of Cardiology of Tianjin First Center Hospital

Received Date: 10 January 2015

摘要

摘要: 心力衰竭的发生、发展与交感神经系统活性增加有关。近年来出现的肾去交感神经术(RDN)可通过选择性阻断肾脏传入和传出神经活性达到降压的目的,成为治疗顽固性高血压的新手段。RDN除了拥有良好的降压效果外,还具有减慢心率、减轻左室肥厚、改善心功能、减少尿蛋白等作用。因此,RDN对于伴有心血管疾病的患者可能同样具有较好的治疗作用。现将对RDN在心力衰竭治疗中的作用及研究现状做一综述。
- 心力衰竭 /
- 肾去交感神经术 /
- 交感神经系统
Abstract: Heart failure is associated with activation of the sympathetic nervous system.Renal denervation has been developed in order to decrease blood pressure in resistant hypertension by a reduction in renal afferent and efferent sympathetic nerve activity.In addition to reducing blood pressure,it is able to reduce heart rate and left ventricular hypertrophy,improve cardiac function,and ameliorate albuminuria.Therefore,renal denervation is a promising technique that may improve the outcome of patients with sympathetic hyperactivity and cardiovascular diseases.This article will review the renal denervation in treatment of heart failure.
- heart failure /
- renal denervation /
- sympathetic nervous system

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