Joint hypothesis: a novel concept of cholesterol, inflammation, and atherosclerosis
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摘要: 动脉粥样硬化(AS)之胆固醇学说已深入人心，炎症作为AS发病的重要机制之一也倍受关注。新近Nature杂志刊出哈佛大学Peter Libby教授的文章，其核心学术思想之一是将AS的胆固醇理论和炎症学说“融合”一体，认为二者缺一不可。作者读后颇有感悟，草起此文，与读者共享。Abstract: It is well-known that atherosclerosis (AS) is a cholesterol-mediated disease, strongly associated with inflammation, to which close attention is widely paid. More recently, an interesting paper written by Peter Libby, a professor at Harvard University, was published in Nature. One of the core academic points is the combined theory of cholesterol and inflammation in the development of AS. I have several reactions after reading this wonderful manuscript and now present them in this journal to enjoy it with others.
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Key words:
- atherosclerosis /
- cholesterol /
- inflammation /
- joint hypothesis
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